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Advances in soft-tissue reconstruction and aesthetic surgery have expanded the options available for patients seeking volume restoration and contour refinement. One such development is Alloclae®, an acellular adipose-derived matrix that can be used in select fat grafting applications. It offers an alternative to traditional fat grafting or synthetic fillers for appropriately selected patients.

This article provides an educational overview of Alloclae®, including how it differs from traditional fat grafting, its potential uses, and considerations for recovery. At Colorado Plastic Surgery Center, Alloclae® is offered as part of a broader, individualized approach to aesthetic care.

What Is Alloclae®?

Alloclae® is a structural adipose filler derived from purified donor human fat tissue. Through a multi-step processing method, cellular components are removed while preserving the extracellular matrix (ECM), collagen framework, and naturally occurring growth factors found in adipose tissue. The result is a biocompatible scaffold designed to support soft-tissue volume and gradual tissue integration. Alloclae® undergoes an advanced sterilization process that reduces residual DNA levels well below FDA guidelines for biological products, helping to minimize the risk of an inflammatory response. This process also reduces the free oil fraction to less than 2%, which may lower the risk of oil cyst formation compared with autologous fat grafting.

Once placed, Alloclae® functions as a scaffold that supports tissue remodeling as the body incorporates it. Initial volume is visible at the time of treatment. Over the following months, the scaffold supports tissue remodeling and collagen formation as the body incorporates the matrix. For patients seeking larger-volume enhancement, treatment may be staged, with careful layering over multiple sessions spaced approximately 12–16 weeks apart.

How Alloclae® Differs From Traditional Fat Grafting

Traditional fat grafting

  • Requires liposuction to harvest the patient’s own fat
  • Involves two treatment sites (donor and recipient)
  • Typically requires IV sedation or general anesthesia.
  • Longer recovery due to liposuction of a donor site

Alloclae®

  • Uses pre-processed donor adipose tissue
  • Does not require liposuction or a donor site
  • Commonly performed under local anesthesia
  • Results in less downtime

Each approach has appropriate indications depending on anatomy, goals, and tolerance for recovery.

Clinical Uses of Alloclae® at Colorado Plastic Surgery Center

Natural Breast Augmentation and Shape Refinement

Alloclae® may be used for subtle breast volume enhancement, improved upper-pole fullness, or correction of asymmetry. Rather than significantly increasing breast size, this approach is typically suited for patients seeking natural-appearing contour refinement.

In some cases, Alloclae® may also be used adjunctively with other breast procedures or in combination with traditional fat grafting, depending on the patient’s anatomy and goals.

Hip Dips and Body Contour Irregularities

Hip dips are a normal anatomical feature related to skeletal structure and fat distribution. For patients who wish to soften this area, Alloclae® allows for targeted volume placement.

Because no fat harvesting is required, this option may be considered by patients with limited donor fat or those who prefer a less invasive approach.

Treatment Overview

Your journey will start with a comprehensive consultation, allowing Dr. Roider or Dr. Slenkovich to evaluate your anatomy, goals, and specific treatment areas.

The procedure is performed at the Surgery Center of Colorado, our private, state-of-the-art ambulatory surgery center. Because Alloclae® placement can also be performed in a clinic-based setting under local anesthesia, it may be an appropriate option for patients who are not ideal candidates for general anesthesia due to medical or anatomical considerations. The treatment area is cleansed and numbed with local anesthesia. Alloclae® is then carefully placed through one or more small (<1 cm) incisions using a fine cannula, with continuous assessment of contour and symmetry. Incisions are closed with dissolvable sutures, and patients typically return home shortly after the procedure.

Recovery and Downtime

Because Alloclae® does not involve liposuction, recovery is generally limited to the treated area. Patients may experience:

  • Mild swelling or bruising
  • Localized tenderness
  • A brief interruption to normal activities

Many Denver-area patients return to daily routines relatively quickly, though strenuous exercise may be restricted temporarily. Recovery timelines vary based on the treatment area and individual healing response.

Patient Selection and Consultation

Alloclae® is not appropriate for every patient or every indication. A comprehensive consultation is necessary to evaluate a patient's aesthetic goals, anatomy and tissue characteristics, scarring from prior procedures, and overall health and expectations.

However, in general great candidates are healthy individuals who are seeking:

  • Small volume breast augmentation
  • Correction of contour deformities following liposuction
  • Correction of hip dips

At Colorado Plastic Surgery Center, treatment planning emphasizes education, transparency, and individualized decision-making so patients can choose options that align with their goals and comfort level.


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All content on this page was reviewed by Healthcare Chief Operating Officer Stephanie Cooper, MBA, MHA

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