alloClae™ adds natural breast volume without implants, without liposuction, and without general anesthesia.
Medically reviewed by Dr. Laura Roider & Dr. Nick Slenkovich
In this video, Dr. Laura Roider discusses how alloClae™ is providing a new option for patients seeking subtle breast enhancement without implants, liposuction, or traditional surgery.
alloClae™ is a regenerative adipose matrix that acts as a scaffold for your body's natural tissue restoration process. Over time, your body replaces the matrix with its own tissue, helping improve shape, contour, and upper pole fullness.



No. Traditional fat transfer uses your own fat, harvested via liposuction from another part of your body. alloClae™ is donor-derived fat tissue that has been sterilized while preserving the natural 3D honeycomb structure of fat. Because that structure is intact, alloClae™ performs at the application site much like your own fat would. The source and the processing are different from autologous fat grafting, but the underlying tissue structure is similar. alloClae™ does not require liposuction, and the two approaches can also be combined when appropriate.
alloClae™ is suited for modest, natural-looking volume enhancement per session, generally a subtle to moderate improvement rather than a dramatic single-session size change. We typically start with approximately 50 cc per breast per session. For patients seeking larger cumulative volume, alloClae™ can be staged across multiple sessions spaced approximately 12 weeks apart, and it can also be combined with traditional fat grafting in the same session to help achieve a larger result.
Results are long-lasting. Once alloClae™ is incorporated into the body, the placed tissue acts like your own natural fat at that site. Early volume is visible at the time of treatment, with gradual integration continuing over the months that follow. Because the integrated tissue acts like your own fat, significant weight changes can affect your results the same way natural weight fluctuations would change any soft tissue area of the body.
Yes, in select cases. alloClae™ can be used in conjunction with a breast lift, with traditional fat grafting when donor fat alone is insufficient, or placed over implants to camouflage edges and rippling in revision or thin-tissue cases. Whether any combination is appropriate depends on your anatomy and goals. We assess these cases individually.
For most patients, no. alloClae™ placement is performed under local anesthesia with the patient awake and comfortable, which is one of the procedure's practical advantages for patients who want to avoid going under. Case complexity and patient preference may affect the anesthesia approach, which we discuss during your consultation.
That depends on what you are hoping to achieve. alloClae™ is one of several options for breast enhancement (implants, Preservé, traditional fat grafting, or a combination), and the right one is determined by your anatomy and goals, not by process of elimination. The consultation is designed to clarify that. Patients who come in uncertain about implants often leave with a clearer picture of what is and is not possible across all the options available to them.
alloClae™ has a defined safety profile. Like all procedures of this type, complications are possible, although not everyone experiences them. Potential complications include cyst or nodule formation, pain, infection, hematoma, anaphylaxis or other allergic or immune responses, and discoloration of the skin at the procedure site. alloClae™ may not be appropriate for patients with severe allergen sensitivities, a history of anaphylaxis, or active infection. We review your specific risk factors during consultation.
Yes. alloClae™ is a human tissue allograft regulated by the FDA under the framework that applies to processed human cells, tissues, and tissue-based products. This is a different regulatory pathway from synthetic implants or FDA-approved drugs, but it is a defined and active regulatory framework.